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KMID : 1101420160480010036
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Korean Journal of Clinical Laboratory Science
2016 Volume.48 No. 1 p.36 ~ p.40
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Investigation of Red Cell Antiobody Screening Tests Gyeonggi Areas
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Kim Dai-Joong
Sung Hyun-Ho
Park Chang-Eun
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Abstract
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Red blood cell (RBC) alloimmunization results from genetic disparity of RBC antigens between donor and recipients. The discrepancy of RBC antibody screening test occurs when the results of red cell tests do not agree with those of the serum test. In order to select the proper blood units for transfusion, clarification of the cause of discrepancies is essential. The RBC antibody screening test is an easy, quick, and reliable method for detection of clinically significant antibodies. Antibody screening and identification is recommended prior to transfusion to determine whether there is blood group incompatibility. We reported that phenotyping for E, D, M, E+c, and C+e antibody screening test should be extended. Therefore, these results indicate that anti-D and anti-E alloantibodies were major risk factors for haemolytic disease of the newborn or delayed haemolytic transfusion reactions in this study population. We suggested that its antibody screening be adapted to blood safety interventions. Targeted screening of selected recipients at risk offers less value than universal antibody screening, and more research is needed to determine the real incidence of this national condition.
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KEYWORD
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Alloimmunization, Red blood cell antibody screening test, Transfusion
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